Alzheimer’s disease is a progressive condition that affects one in nine senior citizens over 65. While early-stage Alzheimer’s might result in mild memory loss, symptoms of the disease worsen over time and can cause the patient to lose their ability to speak, interact with loved ones or respond to environmental conditions. Alzheimer’s disease has no known cure, and experts can only speculate as to its origin. Medical scientists continue to research and look for answers. The following are some of the updates in Alzheimer’s research from this past year.
Are There Treatments for Alzheimer’s Disease?
Alzheimer’s is identified by abnormal changes in the brain, which experts believe to be caused primarily by plaques and tangles. Plaques are defined as protein fragment deposits that develop in the spaces between nerve cells. Tangles consist of twisted protein fibers that form in the brain of Alzheimer’s patients. Because Alzheimer’s can manifest differently in each person, it is considered unlikely that a single pharmaceutical drug would have the ability to treat all senior citizens living with the disease successfully. Still, Alzheimer’s research and clinical trials have allowed scientists to make significant inroads in understanding the complex issues associated with the disease.
The symptoms of the disease are currently managed via several prescription drugs. However, none of these drugs can cure nor slow the progression of the symptoms.
Alzheimer’s Research Progress
In addition to the recent approval of the controversial drug Aducanumab, medical researchers have made meaningful progress in 2021.
- Scientists from Tokyo Metropolitan University recently discovered an element of a key protein known as tau. The researchers theorize that tau may cause additional protein deposits to amass in the brain, causing a genesis of the disease. While under normal circumstances, the tau protein is essential to the healthy function of cells, when the “cell highways” they create do not form correctly, a broad spectrum of neurodegenerative diseases can occur.
- A current research study at the University of Arizona Health Sciences is targeting the identification of various therapies that may prevent or deter the progression of Alzheimer’s disease. The study is focusing on understanding ApoE4, a significant genetic risk factor that is a crucial element in our body’s metabolization of fat and brain energy. This research study is expected to give researchers a deeper understanding of possible interventions for those in the later stages of Alzheimer’s.
Clinical Trials
According to the Alzheimer’s Association, clinical trials permit scientists to conduct research with human volunteers. This is done to evaluate if a potential treatment is safe and effective for use. Without the participation of volunteers and these clinical trials, there is little hope for prevention, treatment – or ultimately, a cure. New pharmaceutical drugs must undergo a series of test phases before being approved by the FDA.
If you or a senior loved one would like to know more about getting involved in a clinical trial, there are many ways to participate. The first step is to have a consultation with your medical provider. Your physician has an in-depth understanding of your medical history and all variables and may be able to refer you to an appropriate clinical trial.
TrialMatch (operated by the Alzheimer’s Association) connects patients to clinical studies in their region. To utilize TrialMatch, an applicant will be required to provide a clinical diagnosis, the results of diagnostic tests, and any current medications.
Before agreeing to participate in a clinical trial, it’s imperative to work closely with your physician to answer essential questions, including understanding the goal of the study, the risks and potential side effects, the level of participation required of the participant, and the expected effect on daily life. You should also ask if expenses will be reimbursed and if you will be paid.
If your loved one is currently living with Alzheimer’s disease and you are seeking a compassionate and competent memory care center in The Villages, please call A Banyan Residence for more information.
